Synthesis and Structure Determination of µ-Conotoxin PIIIA
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Notably, we show that IMs highly express Factor XIIIA, which promotes fibrin cross-linking to create a scaffold for LUSC cell invasion and metastases. Consistently, human LUSC samples containing extensive cross-linked fibrin in the microenvironment correlated with poor survival. Factor XIII (FXIII) is a key molecule in the field of blood coagulation and in the last decades it has weakened attention within the field of angiogenesis and tissue repair. FXIII positively influences wound healing in several tissues by exerting multiple plasma and cellular functions. Factor XIIIa has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells present in the placenta, uterus, and prostate; it is also present in monocytes, macrophages and dermal dendritic cells. Factor XIII a is an enzyme and as a coagulation factor it is an important part of the blood coagulation cascade.
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Factor XIIIa has also been used with CD34 to Define Factor xiiia. Factor xiiia synonyms, Factor xiiia pronunciation, Factor xiiia translation, English dictionary definition of Factor xiiia. Noun 1. factor XIII - in the clotting of blood thrombin catalyzes factor XIII into its active form which causes fibrin to form a stable clot fibrinase 2007-01-23 · Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot.
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,. 1980. , vol. Rabbit Polyclonal Factor XIIIa antibody [N1N3].
Fil:Human factor XIII 1EVU.png – Wikipedia
This is the second study to show the immunohistochemical profile, with emphasis in FOSL1, of an additional case of symmetrical palatal fibromatosis. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. Definition / general Fibrohistiocytic marker; note that peritumoral cells may also exhibit Factor XIIIa staining Also active form of factor XIII, an enzyme of coagulation system that crosslinks fibrin (Wikipedia: Factor XIII [Accessed 2 August 2018]) Factor XIIIa (FXIIIa) (fibrinoligase, plasma transglutaminase, fibrin stabilizing factor, E.C. 188.8.131.52) is a glutaminyl-peptide γ-glutamyl transferase functioning in the final stages of the coagulation cascade, stabilizing the fibrin clot by crosslinking the α and γ chains of fibrin to form homopolymers (1-4). Factor XIIIa is a blood coagulation prototransglutaminase 1, which becomes an activated component of the final stages of the clotting cascade as a result of the interaction with thrombin and Ca 2+.
However, exceptions occur. Factor XIIIa is a pan-histiocytic marker, similar to CD68. Common Pitfalls [edit | edit source] Not specific for dermatofibroma.
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FC13A : Factor XIIIa, a blood and intracellularly produced coagulation factor, has been found in a variety of cell types, including fibroblast-like mesenchymal Factor XIIIa has also been used with CD34 to differentiate between dermatofibroma and dermatofibrosarcoma protuberans (3). Specifications. Specifications Mouse monoclonal Factor XIIIa antibody [AC-1A1]. Validated in WB, IHC, Flow Cyt and tested in Human.
Factor XIII is the zymogenic form of the glutaminyl-peptide g-glutamyl transferase factor XIIIa (fibrinoligase, plasma transglutaminase, fibrin stabilizing factor, E.C. 184.108.40.206) (1-3). Factor XIII is unique among transamidases in that it is a zymogen in vivo (2). Factor XIIIa antibody Mouse Monoclonal from Proteintech validated in Western Blot (WB), Immunohistochemistry (IHC), Enzyme-linked Immunosorbent Assay (ELISA) applications. This antibody reacts with human, pig, mouse samples. Cat.No.
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Factor XIIIa antibody Mouse Monoclonal from Proteintech validated in Western Blot (WB), Immunohistochemistry (IHC), Enzyme-linked Immunosorbent Assay (ELISA) applications. This antibody reacts with human, pig, mouse samples. Cat.No. 66325-1-Ig. Synonyms for Factor xiiia in Free Thesaurus. Antonyms for Factor xiiia.
Supplied as 50 µg purified protein (2.4 mg/mL). Mouse monoclonal Factor XIIIa antibody [AC-1A1].
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This antibody reacts with human, pig, mouse samples. Cat.No. 66325-1-Ig. Both spindle and pleomorphic tumor cells are consistently positive for vimentin, with varied expression of CD34, factor XIIIa, VEGF, and CD99, but are negative for S100 protein, cytokeratin, desmin, epithelial membrane antigen, smooth muscle actin, HMB-45, MyoD1, p63, and CD31 (determined by immunohistochemistry). Synonyms for Factor xiiia in Free Thesaurus. Antonyms for Factor xiiia. 1 synonym for factor XIII: fibrinase.
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XIIIa is an 9 Mar 2019 Tridegin is a potent and specific 66mer peptide inhibitor of coagulation factor XIIIa with six cysteines involved in three disulfide bonds. Three of S100 protein was expressed by 100% of neurofibromas, schwannomas, and melanocytic nevi. Our findings suggest that factor XIIIa may provide a reliable and Factor XIIIa is a blood proenzyme that has been identified in platelets, megakaryocyte, and fibroblast-like mesenchymal or histiocytic cells present in the Background— Activated factor XIII (FXIIIa) mediates fibrinolytic resistance and is a hallmark of newly formed thrombi. In vivo imaging of FXIIIa activity could 1 Jan 2007 It has been demonstrated recently that coagulation factor XIII (FXIII) plays an extraordinary role in myocardial healing after infarction, improving Buy mouse monoclonal (F13A1/1448) antibody to Factor XIIIa (A248512). Applications: WB, IHC and more. Reactivity: Human. ✔️ FREE Shipping.